Non sedating oral antihistamine Uncensored face to face chat
Bilastine is efficacious in all nasal symptoms including obstruction and in eye symptoms.The observations indicate that non-sedating antihistamines, as opposed to what has been thought previously, may be helpful in patients with allergic rhinitis in whom nasal obstruction is a major concern.
Clinical studies sponsored by the manufacturer have shown that bilastine 20 mg once daily is as efficacious as other nonsedating antihistamines in allergic rhinoconjunctivitis and chronic urticaria in individuals from 12 and 18 years of age, respectively.
Since these effects are not genuine antagonistic but rather represent a balance displacement between active and inactive forms of H1 receptors, now, the term H1 antihistamine rather than the former “antihistamine antagonist” is used .
Non-sedating antihistamines are part of a quite heterogeneous pharmacological group.
Several mediators are involved in the pathophysiology; however, histamine plays a vital role in the allergic immediate reaction .
Once an allergen is introduced to Ig E-sensitized mast cells, a degranulation is triggered which causes histamine to be released.